Disrupted Sleep Homeostasis and Altered Expressions of Clock Genes in Rats with Chronic Lead Exposure

Disrupted Sleep Homeostasis and Altered Expressions of Clock Genes in Rats with Chronic Lead Exposure

Sleep disturbance is one of the neurobehavioral complications of lead neurotoxicity. The present study evaluated the impacts of chronic lead exposure on alteration of the sleep–wake cycle in association with changes of clock gene expression in the hypothalamus. Sprague–Dawley rats with chronic lead...

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Bibliographic Details
Main Authors: Chung-Yao Hsu, Yao-Chung Chuang, Fang-Chia Chang, Hung-Yi Chuang, Terry Ting-Yu Chiou, Chien-Te Lee
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxics
Subjects:
chronic lead exposure
sleep homeostasis
clock genes
neurotoxicity
circadian rhythm
sleep–wake cycle
Online Access:https://www.mdpi.com/2305-6304/9/9/217

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https://www.mdpi.com/2305-6304/9/9/217

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