The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II

The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II

Summary: AT-rich interactive domain-containing proteins 1A and 1B (ARID1A and ARID1B) are mutually exclusive subunits of the chromatin remodeler SWI/SNF. ARID1A is the most frequently mutated chromatin regulator across all cancers, and ovarian clear cell carcinoma (OCCC) carries the highest prevalen...

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Bibliographic Details
Main Authors: Marco Trizzino, Elisa Barbieri, Ana Petracovici, Shuai Wu, Sarah A. Welsh, Tori A. Owens, Silvia Licciulli, Rugang Zhang, Alessandro Gardini
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308933

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http://www.sciencedirect.com/science/article/pii/S2211124718308933

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