Measuring and estimating GFR and treatment effect in ADPKD patients: results and implications of a longitudinal cohort study.

Trials failed to demonstrate protective effects of investigational treatments on glomerular filtration rate (GFR) reduction in Autosomal Dominant Polycystic Kidney Disease (ADPKD). To assess whether above findings were explained by unreliable GFR estimates, in this academic study we compared GFR val...

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Main Authors: Piero Ruggenenti, Flavio Gaspari, Antonio Cannata, Fabiola Carrara, Claudia Cella, Silvia Ferrari, Nadia Stucchi, Silvia Prandini, Bogdan Ene-Iordache, Olimpia Diadei, Norberto Perico, Patrizia Ondei, Antonio Pisani, Erasmo Buongiorno, Piergiorgio Messa, Mauro Dugo, Giuseppe Remuzzi, GFR-ADPKD Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22393413/pdf/?tool=EBI