Synthesis of triazole-containing ciprofloxacin conjugate and its in silico test as a cytochrome P450 ligand

Cytochromes P450 are hem-containing monooxygenases which catalyse biosynthesis of many compounds playing an essential role in cellular functions as well as degradation of drugs and xenobiotics. Some P450s (e. g., human CYP19 and CYP17, fungal CYP51) are valid target proteins for some drugs. The othe...

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Bibliographic Details
Main Authors: Yaroslav V. Faletrov, Liliya I. Glinskaya, Matvey S. Horetski, Jan V. Panada, Nina S. Frolova, Vladimir M. Shkumatov
Format: Article
Language:Belarusian
Published: Belarusian State University 2021-04-01
Series:Журнал Белорусского государственного университета: Химия
Subjects:
Online Access:https://journals.bsu.by/index.php/chemistry/article/view/3582