Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice.

Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice.

Senile plaques and neurofibrillary tangles are major neuropathological features of Alzheimer's Disease (AD), however neuronal loss is the alteration that best correlates with cognitive impairment in AD patients. Underlying neurotoxic mechanisms are not completely understood although specific ne...

Full description

Bibliographic Details
Main Authors: Juan Jose Ramos-Rodriguez, Sara Molina-Gil, Raquel Rey-Brea, Esther Berrocoso, Monica Garcia-Alloza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24278223/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24278223/pdf/?tool=EBI

Similar Items