Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

Abstract Background Microglial activation contributes to the neuropathology associated with chronic alcohol exposure and withdrawal, including the expression of inflammatory and anti-inflammatory genes. In the current study, we examined the transcriptome of primary rat microglial cells following inc...

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Bibliographic Details
Main Authors: Sergey Kalinin, Marta González-Prieto, Hannah Scheiblich, Lucia Lisi, Handojo Kusumo, Michael T. Heneka, Jose L. M. Madrigal, Subhash C. Pandey, Douglas L. Feinstein
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Neuroinflammation
Subjects:
Alcohol
Phagocytosis
Complement
Alzheimer’s disease
Amyloid
Microglia
Online Access:http://link.springer.com/article/10.1186/s12974-018-1184-7

Internet

http://link.springer.com/article/10.1186/s12974-018-1184-7

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