The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection.

Clostridium difficile is the main agent responsible for hospital acquired antibiotic associated diarrhoea. In recent years, epidemic strains have emerged causing more severe infections. Whilst C. difficile has two major virulence factors, toxins TcdA and TcdB, it is generally accepted that other vir...

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Bibliographic Details
Main Authors: Amira Barketi-Klai, Marc Monot, Sandra Hoys, Sylvie Lambert-Bordes, Sarah A Kuehne, Nigel Minton, Anne Collignon, Bruno Dupuy, Imad Kansau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026244?pdf=render