Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease

Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease

Cerebellar hypoplasia is a major characteristic of the Down syndrome (DS) brain. However, the consequences of trisomy upon cerebellar Purkinje cells (PC) and interneurons in DS are unclear. The present study performed a quantitative and qualitative analysis of cerebellar neurons immunostained with a...

Full description

Bibliographic Details
Main Authors: Jennifer C. Miguel, Sylvia E. Perez, Michael Malek-Ahmadi, Elliott J. Mufson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Down syndrome
Alzheimer's disease
cerebellum
calcium binding proteins
Purkinje cells
nerve growth factor receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.645334/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.645334/full

Similar Items