2D-quantitative structure–activity relationships model using PLS method for anti-malarial activities of anti-haemozoin compounds

2D-quantitative structure–activity relationships model using PLS method for anti-malarial activities of anti-haemozoin compounds

Abstract Background Emergence of cross-resistance to current anti-malarial drugs has led to an urgent need for identification of potential compounds with novel modes of action and anti-malarial activity against the resistant strains. One of the most promising therapeutic targets of anti-malarial age...

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Bibliographic Details
Main Authors: Phuong Thuy Viet Nguyen, Truong Van Dat, Shusaku Mizukami, Duy Le Hoang Nguyen, Farhana Mosaddeque, Son Ngoc Kim, Duy Hoang Bao Nguyen, Oanh Thi Đinh, Tu Linh Vo, Giang Le Tra Nguyen, Cuong Quoc Duong, Satoshi Mizuta, Dao Ngoc Hien Tam, M. Phuong Truong, Nguyen Tien Huy, Kenji Hirayama
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Malaria Journal
Subjects:
Antimalarial
Anti-haemozoin
In silico
Quantitative structure–activity relationship
QSAR
Online Access:https://doi.org/10.1186/s12936-021-03775-2

Internet

https://doi.org/10.1186/s12936-021-03775-2

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