RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate

RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate

mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs) that determine mRNA fate, thereby influencing multiple cellular functions across biological contexts. Here, we review the interplay between six well-known RBPs (TTP, AUF-1, KSRP, HuR, TIA-1, and TIAR) that recogn...

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Bibliographic Details
Main Authors: Sofía M. García-Mauriño, Francisco Rivero-Rodríguez, Alejandro Velázquez-Cruz, Marian Hernández-Vellisca, Antonio Díaz-Quintana, Miguel A. De la Rosa, Irene Díaz-Moreno
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
mRNA fate
post-transcriptional regulation
RNA binding proteins
stability
translation
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00071/full

Internet

http://journal.frontiersin.org/article/10.3389/fmolb.2017.00071/full

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