Increased GM‐CSF‐producing NCR‐ ILC3s and neutrophils in the intestinal mucosa exacerbate inflammatory bowel disease

Increased GM‐CSF‐producing NCR‐ ILC3s and neutrophils in the intestinal mucosa exacerbate inflammatory bowel disease

Abstract Objectives Inflammatory bowel disease (IBD) is characterised by dysregulated mucosal immune responses associated with genetic, environmental and microbial factors. Recent therapies targeting key inflammatory mediators such as tumor necrosis factor (TNF)‐α emphasise the importance of innate...

Full description

Bibliographic Details
Main Authors: Yuna Chang, Ju Whi Kim, Siyoung Yang, Doo Hyun Chung, Jae Sung Ko, Jin Soo Moon, Hye Young Kim
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
granulocyte
Inflammatory bowel diseases
innate lymphoid cells
macrophage colony‐stimulating factor
neutrophils
Online Access:https://doi.org/10.1002/cti2.1311

Internet

https://doi.org/10.1002/cti2.1311

Similar Items