Micro Three-Dimensional Neuronal Cultures Generate Developing Cortex-Like Activity Patterns

Studies aimed at neurological drug discovery have been carried out both in vitro and in vivo. In vitro cell culture models have showed potential as drug testing platforms characterized by high throughput, low cost, good reproducibility and ease of handling and observation. However, in vitro neuronal...

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Bibliographic Details
Main Authors: Yixuan Ming, Md Fayad Hasan, Svetlana Tatic-Lucic, Yevgeny Berdichevsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.563905/full