Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling.

Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling.

The Twist1-family basic helix-loop-helix (bHLH) transcription factors including Twist1, Hand1 and Hand2, play an essential role in heart development and are implicated in pathological heart remodeling. Previously, it was reported that these bHLH transcription factors can be regulated by phosphorylat...

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Bibliographic Details
Main Authors: Shuangshuang Lu, Junwei Nie, Qing Luan, Qiuting Feng, Qi Xiao, Zai Chang, Congjia Shan, Daniel Hess, Brian A Hemmings, Zhongzhou Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084786?pdf=render

Internet

http://europepmc.org/articles/PMC3084786?pdf=render

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