Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

Monitoring DNA binding and single-base mismatches accurately in real time is difficult, especially for miniaturized devices. Here the authors report a graphene field-effect transistor array capable of reliably measuring DNA hybridization kinetics and affinity at the picomolar level.

Bibliographic Details
Main Authors: Shicai Xu, Jian Zhan, Baoyuan Man, Shouzhen Jiang, Weiwei Yue, Shoubao Gao, Chengang Guo, Hanping Liu, Zhenhua Li, Jihua Wang, Yaoqi Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14902

Internet

https://doi.org/10.1038/ncomms14902

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