Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue

Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue

<p>Abstract</p> <p>Background</p> <p>Analysis of key therapeutic targets such as epidermal growth factor receptor (EGFR) in clinical tissue samples is typically done by immunohistochemistry (IHC) and is only subjectively quantitative through a narrow dynamic range. The...

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Bibliographic Details
Main Authors: Hembrough Todd, Thyparambil Sheeno, Liao Wei-Li, Darfler Marlene M, Abdo Joseph, Bengali Kathleen M, Taylor Paul, Tong Jiefei, Lara-Guerra Humberto, Waddell Thomas K, Moran Michael F, Tsao Ming-Sound, Krizman David B, Burrows Jon
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Clinical Proteomics
Subjects:
Formalin fixed
FFPE
EGFR
Gefitinib
Targeted therapy
Patient tissue
Quantitative
Personalized medicine
Molecular diagnostics
Non-small cell lung cancer
Online Access:http://www.clinicalproteomicsjournal.com/content/9/1/5

Internet

http://www.clinicalproteomicsjournal.com/content/9/1/5

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