The Role of chk2 in Response to DNA Damage in Cancer Cells
Accumulation of gene changes and chromosomal instability in response to cellular DNA damage lead to cancer. DNA damage induces cell cycle checkpoints pathways. Checkpoints regulate DNA replication and cell cycle progression, chromatin restructuring, and apoptosis. Checkpoint kinase 2 (chk2) is activ...
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| Format: | Article |
| Language: | English |
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University of Mazandaran
2015-03-01
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| Series: | Journal of Genetic Resources |
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| Online Access: | http://sc.journals.umz.ac.ir/article_1115_2ac642bab3bc57fdfbee0371c0d9960b.pdf |