Diabetes Increases the Vulnerability of the Cardiac Mitochondrial Network to Criticality

Diabetes Increases the Vulnerability of the Cardiac Mitochondrial Network to Criticality

Mitochondrial criticality describes a state in which the mitochondrial cardiac network under intense oxidative stress becomes very sensitive to small perturbations, leading from local to cell-wide depolarization and synchronized oscillations that may escalate to the myocardial syncytium generating a...

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Bibliographic Details
Main Authors: Larissa Vetter, Sonia Cortassa, Brian O’Rourke, Antonis A. Armoundas, Djahida Bedja, Johann M. E. Jende, Martin Bendszus, Nazareno Paolocci, Steven J. Sollot, Miguel A. Aon, Felix T. Kurz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
type 1 diabetes
cardiac myocyte
mitochondrial criticality
mitochondria
wavelet analysis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00175/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00175/full

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