The Prognostic Value of the DNA Repair Gene Signature in Head and Neck Squamous Cell Carcinoma

The Prognostic Value of the DNA Repair Gene Signature in Head and Neck Squamous Cell Carcinoma

PurposeTo construct a prognostic signature composed of DNA repair genes to effectively predict the prognosis of patients with head and neck squamous cell carcinoma (HNSCC).MethodsAfter downloading the transcriptome and clinical data of HNSCC from the Cancer Genome Atlas (TCGA), 499 patients with HNS...

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Bibliographic Details
Main Authors: Ruijie Ming, Enhao Wang, Jiahui Wei, Jinxiong Shen, Shimin Zong, Hongjun Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
head and neck squamous cell carcinoma
DNA repair gene
prognostic signature
immune microenvironment
tumor mutation burden
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.710694/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.710694/full

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