Essential Oil from the Leaves of <em>Chromolaena odorata</em>, and Sesquiterpene Caryophyllene Oxide Induce Sedative Activity in Mice

<i>Chromolaena odorata</i> (L.) R.M.King & H.Rob. essential oil (COEO) was investigated for its sedative activity in mice. The results showed that COEO significantly reduced mice locomotor activity and the most efficient concentrations were 0.04 and 0.00004 mg/cage (volume of the cag...

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Bibliographic Details
Main Authors: Godfried Dougnon, Michiho Ito
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/7/651