HIV-DNA in the genital tract of women on long-term effective therapy is associated to residual viremia and previous AIDS-defining illnesses.

OBJECTIVES: To assess the impact of long-term combined antiretroviral therapy (cART) on HIV-RNA and HIV-DNA levels in cervicovaginal secretions of HIV-1-infected women with sustained undetectable plasma RNA viral load (PVL); to explore factors predictive of residual viral shedding; and to evaluate t...

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Bibliographic Details
Main Authors: Thierry Prazuck, Antoine Chaillon, Véronique Avettand-Fènoël, Anne-Laure Caplan, Collins Sayang, Aurélie Guigon, Mohamadou Niang, Francis Barin, Christine Rouzioux, Laurent Hocqueloux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3749193?pdf=render