Metformin Enhances Excitatory Synaptic Transmission onto Hippocampal CA1 Pyramidal Neurons

Metformin Enhances Excitatory Synaptic Transmission onto Hippocampal CA1 Pyramidal Neurons

Metformin (Met) is a first-line drug for type 2 diabetes mellitus (T2DM). Numerous studies have shown that Met exerts beneficial effects on a variety of neurological disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’s disease (HD). However, it is still largely un...

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Bibliographic Details
Main Authors: Wen-Bing Chen, Jiang Chen, Zi-Yang Liu, Bin Luo, Tian Zhou, Er-Kang Fei
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Brain Sciences
Subjects:
metformin
glutamate release
neuronal excitability
hippocampal
pyramidal neurons
Online Access:https://www.mdpi.com/2076-3425/10/10/706

Internet

https://www.mdpi.com/2076-3425/10/10/706

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