The Role of Cyclooxygenase-2 in Cell Proliferation and Cell Death in Human Malignancies

It is well admitted that the link between chronic inflammation and cancer involves cytokines and mediators of inflammatory pathways, which act during the different steps of tumorigenesis. The cyclooxygenases (COXs) are a family of enzymes, which catalyze the rate-limiting step of prostaglandin biosy...

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Bibliographic Details
Main Authors: Cyril Sobolewski, Claudia Cerella, Mario Dicato, Lina Ghibelli, Marc Diederich
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2010/215158