BMP-7 does not protect against bleomycin-induced lung or skin fibrosis.

Bone morphogenic protein (BMP)-7 is a member of the BMP family which are structurally and functionally related, and part of the TGFbeta super family of growth factors. BMP-7 has been reported to inhibit renal fibrosis and TGFbeta1-induced epithelial-mesenchymal transition (EMT), in part through nega...

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Bibliographic Details
Main Authors: Lynne A Murray, Tillie L Hackett, Stephanie M Warner, Furquan Shaheen, Rochelle L Argentieri, Paul Dudas, Francis X Farrell, Darryl A Knight
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19112509/?tool=EBI