DNA specificity determinants associate with distinct transcription factor functions.

To elucidate how genomic sequences build transcriptional control networks, we need to understand the connection between DNA sequence and transcription factor binding and function. Binding predictions based solely on consensus predictions are limited, because a single factor can use degenerate sequen...

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Bibliographic Details
Main Authors: Peter C Hollenhorst, Katherine J Chandler, Rachel L Poulsen, W Evan Johnson, Nancy A Speck, Barbara J Graves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2787013?pdf=render