Screening for familial APP mutations in sporadic cerebral amyloid angiopathy.

Screening for familial APP mutations in sporadic cerebral amyloid angiopathy.

Advances in genetic technology have revealed that variation in the same gene can cause both rare familial and common sporadic forms of the same disease. Cerebral amyloid angiopathy (CAA), a common cause of symptomatic intracerebral hemorrhage (ICH) in the elderly, can also occur in families in an au...

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Bibliographic Details
Main Authors: Alessandro Biffi, Anna Plourde, Yiping Shen, Robert Onofrio, Eric E Smith, Matthew Frosch, Claudia M Prada, James Gusella, Steven M Greenberg, Jonathan Rosand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2978718?pdf=render

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http://europepmc.org/articles/PMC2978718?pdf=render

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