Rapid High Performance Liquid Chromatography Determination and Optimization of Extraction Parameters of the α-Asarone Isolated from Perilla frutescens L.

Rapid High Performance Liquid Chromatography Determination and Optimization of Extraction Parameters of the α-Asarone Isolated from Perilla frutescens L.

Response surface methodology (RSM), based on a central composite design, was used to determine the best liquid-to-raw material ratio (10:3–15 mL/g), extraction time (1–3 h), and ethanol concentration (50%–100%) for maximum content of α-asarone from Perilla frutescens (PF) extract. Experimental value...

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Bibliographic Details
Main Authors: Seung Hwan Hwang, Shin Hwa Kwon, Young-Hee Kang, Jae-Yong Lee, Soon Sung Lim
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
Perilla frutescens L.
α-asarone
validation
optimization
response surface methodology
HPLC
Online Access:http://www.mdpi.com/1420-3049/22/2/270

Internet

http://www.mdpi.com/1420-3049/22/2/270

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