Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis

Promoter engineering enables overproduction of foreign proteins from a single copy expression cassette in Bacillus subtilis

Abstract Background Bacillus subtilis is developed to be an attractive expression host to produce both secreted and cytoplasmic proteins owing to its prominent biological characteristics. Chromosomal integration is a stable expression strategy while the expression level is not ideal compared with pl...

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Bibliographic Details
Main Authors: Chaoyang Zhou, Bin Ye, Shan Cheng, Leizhen Zhao, Yuanxin Liu, Jiandong Jiang, Xin Yan
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Microbial Cell Factories
Subjects:
Bacillus subtilis
Promoter engineering
Chromosomal integration
Highly expression
Online Access:http://link.springer.com/article/10.1186/s12934-019-1159-0

Internet

http://link.springer.com/article/10.1186/s12934-019-1159-0

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