The importance of tau phosphorylation for neurodegenerative diseases

Fibrillar deposits of highly phosphorylated tau are a key pathological feature of several neurodegenerative tauopathies including Alzheimer’s disease and some frontotemporal dementias. Increasing evidence suggests that the presence of these end-stage neurofibrillary lesions do not cause neuronal los...

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Bibliographic Details
Main Authors: Wendy eNoble, Diane P Hanger, Christopher CJ Miller, Simon eLovestone
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00083/full