Impact of JNK and Its Substrates on Dendritic Spine Morphology

Impact of JNK and Its Substrates on Dendritic Spine Morphology

The protein kinase JNK1 exhibits high activity in the developing brain, where it regulates dendrite morphology through the phosphorylation of cytoskeletal regulatory proteins. JNK1 also phosphorylates dendritic spine proteins, and <i>Jnk1-/-</i> mice display a long-term depression defici...

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Bibliographic Details
Main Authors: Emilia Komulainen, Artemis Varidaki, Natalia Kulesskaya, Hasan Mohammad, Christel Sourander, Heikki Rauvala, Eleanor T. Coffey
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
jnk1
jnk
synaptic plasticity
dendritic spine
substrate
hippocampus
dcx
marcksl1
mrp
morris water maze
Online Access:https://www.mdpi.com/2073-4409/9/2/440

Internet

https://www.mdpi.com/2073-4409/9/2/440

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