Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner

Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner

Background: Tissue factor (TF) combined with its ligand FVII initiates blood coagulation and intracellular signaling. Obese and type 2 diabetic subjects have increased TF expression in their adipose tissue and an increased risk for thrombotic complications. Here we address the role of TF/FVII on adi...

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Bibliographic Details
Main Authors: Desirée Edén, Grigorios Panagiotou, Dariush Mokhtari, Jan W. Eriksson, Mikael Åberg, Agneta Siegbahn
Format: Article
Language:English
Published: Upsala Medical Society 2019-07-01
Series:Upsala Journal of Medical Sciences
Subjects:
adipocytes
coagulation
fvii
lipolysis
tissue factor
Online Access:http://dx.doi.org/10.1080/03009734.2019.1645248

Internet

http://dx.doi.org/10.1080/03009734.2019.1645248

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