Suppression of neurite outgrowth by high-dose nerve growth factor is independent of functional p75NTR receptors

We have previously demonstrated that high concentrations of nerve growth factor suppress neurite outgrowth from sensory neurons. Inhibition could be mediated by either the p75NTR or TrkA receptor. We used a functional block of p75NTR by REX antibody in rat dorsal root ganglion neurons and dorsal roo...

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Bibliographic Details
Main Authors: Anna M. Conti, Stephen Brimijoin, Laurence J. Miller, Anthony J. Windebank
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001992