pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma

pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma

Interfering with tumor metabolism is an emerging strategy for treating cancers that are resistant to standard therapies. Featuring a rapid proliferation rate and exacerbated glycolysis, hepatocellular carcinoma (HCC) creates a highly hypoxic microenvironment with excessive production of lactic and c...

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Bibliographic Details
Main Authors: Olga Kuchuk, Alessandra Tuccitto, Davide Citterio, Veronica Huber, Chiara Camisaschi, Massimo Milione, Barbara Vergani, Antonello Villa, Malcolm Ronald Alison, Simone Carradori, Claudiu T Supuran, Licia Rivoltini, Chiara Castelli, Vincenzo Mazzaferro
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:OncoImmunology
Subjects:
hepatocellular carcinoma
ph regulatory molecules
therapy
tumor microenvironment
immunosuppressive cells
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1445452

Internet

http://dx.doi.org/10.1080/2162402X.2018.1445452

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