NP-59 Adrenal Scintigraphy as an Imaging Biomarker to Predict KCNJ5 Mutation in Primary Aldosteronism Patients

NP-59 Adrenal Scintigraphy as an Imaging Biomarker to Predict KCNJ5 Mutation in Primary Aldosteronism Patients

PurposeSomatic KCNJ5 mutation occurs in half of unilateral primary aldosteronism (PA) and is associated with more severe phenotype. Mutation status can only be identified by tissue sample from adrenalectomy. NP-59 adrenal scintigraphy is a noninvasive functional study for disease activity assessment...

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Bibliographic Details
Main Authors: Ching-Chu Lu, Ruoh-Fang Yen, Kang-Yung Peng, Jei-Yie Huang, Kwan-Dun Wu, Jeff S. Chueh, Wan-Yu Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Endocrinology
Subjects:
primary aldosteronism
NP-59 adrenal scintigraphy
KCNJ5
semiquantification
mutation prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.644927/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.644927/full

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