Metabolic Shift Induced by ω -3 PUFAs and Rapamycin Lead to Cancer Cell Death

Metabolic Shift Induced by ω -3 PUFAs and Rapamycin Lead to Cancer Cell Death

Background/Aims: Rapamycin (Rp), the main mammalian target of rapamycin complex inhibitor, is a promising therapeutic agent for breast cancer. However, metabolic disorders and drug resistance reduce its efficacy. Epidemiological, clinical, and experimental studies have demonstrated that omega-3 poly...

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Bibliographic Details
Main Authors: Shenglong Zhu, Ninghan Feng, Guangxiao Lin, Yuelin Tong, Xuan Jiang, Qin Yang, Shunhe Wang, Wei Chen, Zhao He, Yong Q Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Rapamycin
ω-3 PUFAs
Cancer metabolism
Breast cancer
Online Access:https://www.karger.com/Article/FullText/492648

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https://www.karger.com/Article/FullText/492648

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