Enhancement of Outward Potassium Current May Participate in β-Amyloid Peptide-Induced Cortical Neuronal Death

In light of recent evidence implicating the upregulation of outward K+current in mediating several forms of neuronal apoptosis, we tested the hypothesis that such an upregulation might specifically contribute to the pathogenesis of β-amyloid peptide (Aβ)-induced neuronal death. Exposure to Aβ fragme...

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Bibliographic Details
Main Authors: Shan Ping Yu, Z.Shadi Farhangrazi, Howard S. Ying, Chen-Hsiung Yeh, Dennis W. Choi
Format: Article
Language:English
Published: Elsevier 1998-08-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996198901863