Synthesis and Initial In Vivo Evaluation of [<sup>11</sup>C]AZ683—A Novel PET Radiotracer for Colony Stimulating Factor 1 Receptor (CSF1R)

Positron emission tomography (PET) imaging of Colony Stimulating Factor 1 Receptor (CSF1R) is a new strategy for quantifying both neuroinflammation and inflammation in the periphery since CSF1R is expressed on microglia and macrophages. AZ683 has high affinity for CSF1R (K<i><sub>i</s...

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Bibliographic Details
Main Authors: Sean S. Tanzey, Xia Shao, Jenelle Stauff, Janna Arteaga, Phillip Sherman, Peter J. H. Scott, Andrew V. Mossine
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/11/4/136