Genetically encoded optical sensors for monitoring of intracellular chloride and chloride-selective channel activity

This review briefly discusses the main approaches for monitoring chloride (Cl−), the most abundant physiological anion. Noninvasive monitoring of intracellular Cl− ([Cl−]i) is a challenging task owing to two main difficulties: (i) the low transmembrane ratio for Cl&...

Full description

Bibliographic Details
Main Authors: Piotr Bregestovski, Tatyana Waseem, Marat Mukhtarov
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.02.015.2009/full