Focus on Clozapine Withdrawal- and Misuse-Related Cases as Reported to the European Medicines Agency (EMA) Pharmacovigilance Database

Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although the molecule presents with a range of well-known side-effects, its discontinuation/withdrawal syndrome has been only anecd...

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Bibliographic Details
Main Authors: Stefania Chiappini, Fabrizio Schifano, John Martin Corkery, Amira Guirguis
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/10/2/105