Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity

The daily rhythm of cortisol secretion is relatively stable and primarily under the influence of the circadian clock. Nevertheless, several other factors affect hypothalamo-pituitary-adrenal (HPA) axis activity. Sleep has modest but clearly detectable modulatory effects on HPA axis activity. Sleep o...

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Bibliographic Details
Main Authors: Marcella Balbo, Rachel Leproult, Eve Van Cauter
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2010/759234