Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.

Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.

Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer's disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS)....

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Bibliographic Details
Main Authors: Tian Yu, Matthew D Taussig, Nicholas V DiPatrizio, Giuseppe Astarita, Daniele Piomelli, Bryan C Bergman, Mark L Dell'Acqua, Robert H Eckel, Hong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4532501?pdf=render

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http://europepmc.org/articles/PMC4532501?pdf=render

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