Regulation of extracellular bioactive cations in bone tissue microenvironment induces favorable osteoimmune conditions to accelerate in situ bone regeneration

Regulation of extracellular bioactive cations in bone tissue microenvironment induces favorable osteoimmune conditions to accelerate in situ bone regeneration

The design of orthopedic biomaterials has gradually shifted from “immune-friendly” to “immunomodulatory,” in which the biomaterials are able to modulate the inflammatory response via macrophage polarization in a local immune microenvironment that favors osteogenesis and implant-to-bone osseointegrat...

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Bibliographic Details
Main Authors: Zhengjie Lin, Danni Shen, Weixiao Zhou, Yufeng Zheng, Tiantian Kong, Xuanyong Liu, Shuilin Wu, Paul K. Chu, Ying Zhao, Jun Wu, Kenneth M.C. Cheung, Kelvin W.K. Yeung
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-08-01
Series:Bioactive Materials
Subjects:
Bone regeneration
Osteoimmunomodulatory property
Osteoimmune environment
Macrophage polarization
Magnesium ions
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000293

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http://www.sciencedirect.com/science/article/pii/S2452199X21000293

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