Regulation of extracellular bioactive cations in bone tissue microenvironment induces favorable osteoimmune conditions to accelerate in situ bone regeneration
The design of orthopedic biomaterials has gradually shifted from “immune-friendly” to “immunomodulatory,” in which the biomaterials are able to modulate the inflammatory response via macrophage polarization in a local immune microenvironment that favors osteogenesis and implant-to-bone osseointegrat...
Main Authors: | Zhengjie Lin, Danni Shen, Weixiao Zhou, Yufeng Zheng, Tiantian Kong, Xuanyong Liu, Shuilin Wu, Paul K. Chu, Ying Zhao, Jun Wu, Kenneth M.C. Cheung, Kelvin W.K. Yeung |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2021-08-01
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Series: | Bioactive Materials |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X21000293 |
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