Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway

Abstract Background To clarify the role of apolipoprotein D (Apod) in alleviating glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells (MSCs) via the PI3K/Akt pathway, thus influencing the progression of osteoporosis (OP). Methods Osteogenesis in MSCs was induced by...

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Bibliographic Details
Main Authors: Rong-Hua Yu, Xiang-yang Zhang, Wei Xu, Zhi-kun Li, Xiao-dong Zhu
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Apod
MSCs
PI3K/Akt
Osteogenesis
Online Access:http://link.springer.com/article/10.1186/s13018-020-01824-1

Internet

http://link.springer.com/article/10.1186/s13018-020-01824-1

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