An integration-free iPSC line, ICCSICi007-A, derived from a female Alzheimer's disease patient with the APOE-ε4/ε4 alleles

The epsilon4 (ε4) allele of the APOE gene, which encodes the apolipoprotein E4 (ApoE4), is the strongest genetic risk factor known for late-onset Alzheimer´s disease (LOAD). Here, we present the characterization of an iPSC line generated from dermal fibroblasts of a female AD patient using Sendai vi...

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Bibliographic Details
Main Authors: Eva Díaz-Guerra, Eva Rodríguez-Traver, Elena P. Moreno-Jiménez, Itziar de Rojas, César Rodríguez, María Orera, Isabel Hernández, Agustín Ruiz, Carlos Vicario
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119302181