Differential placental DNA methylation of VEGFA and LEP in small-for-gestational age fetuses with an abnormal cerebroplacental ratio.

Differential placental DNA methylation of VEGFA and LEP in small-for-gestational age fetuses with an abnormal cerebroplacental ratio.

<h4>Background</h4>In Fetal Growth Restriction 'fetal programming' may take place via DNA methylation, which has implications for short-term and long-term health outcomes. Small-for-gestational age fetuses are considered fetal growth restricted, characterized by brain-sparing w...

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Main Authors: Iris Bekkering, Mariëtte Leeuwerke, Jozien C Tanis, Mirthe H Schoots, Rikst Nynke Verkaik-Schakel, Torsten Plösch, Caterina M Bilardo, Jasper J H Eijsink, Arend F Bos, Sicco A Scherjon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221972

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https://doi.org/10.1371/journal.pone.0221972

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