Mcm10 proteolysis initiates before the onset of M-phase

<p>Abstract</p> <p>Background</p> <p>Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubi...

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Bibliographic Details
Main Authors: Khan Muntaz, Sharma Aparna, Kaur Manpreet, Kar Ananya, Saxena Sandeep
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/84