Functional Characterization of a Novel Variant of the Constitutive Androstane Receptor (CAR, NR1I3)

Functional Characterization of a Novel Variant of the Constitutive Androstane Receptor (CAR, NR1I3)

The nuclear receptor constitutive androstane receptor (CAR; NR1I3) controls the inducible expression of many enzymes and transporters involved in drug metabolism and transport, energy metabolism and toxicity. Single nucleotide variants of CAR are quite rare and usually associated with changes in pha...

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Bibliographic Details
Main Authors: Viktoria Prantner, Yuval Cinnamon, Jenni Küblbeck, Ferdinand Molnár, Paavo Honkakoski
Format: Article
Language:English
Published: KenzPub 2018-10-01
Series:Nuclear Receptor Research
Subjects:
NR1I3
single nucleotide variant
Kleefstra syndrome
co-activator
recruitment
Online Access:http://www.kenzpub.com/journals/nurr/2018/101386/

Internet

http://www.kenzpub.com/journals/nurr/2018/101386/

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