Regulation of mTORC1 by Upstream Stimuli

The mammalian target of rapamycin (mTOR) is an evolutionary conserved Ser/Thr protein kinase that senses multiple upstream stimuli to control cell growth, metabolism, and autophagy. mTOR is the catalytic subunit of mTOR complex 1 (mTORC1). A significant amount of research has uncovered the signaling...

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Bibliographic Details
Main Authors: Chase H. Melick, Jenna L. Jewell
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/9/989