Metabolic plasticity in resting and thrombin activated platelets.

Platelet thrombus formation includes several integrated processes involving aggregation, secretion of granules, release of arachidonic acid and clot retraction, but it is not clear which metabolic fuels are required to support these events. We hypothesized that there is flexibility in the fuels that...

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Bibliographic Details
Main Authors: Saranya Ravi, Balu Chacko, Hirotaka Sawada, Philip A Kramer, Michelle S Johnson, Gloria A Benavides, Valerie O'Donnell, Marisa B Marques, Victor M Darley-Usmar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395425?pdf=render