Cancer: a mirrored room between tumor bulk and tumor microenvironment

Abstract It has been well documented that the tumor microenvironment (TME) plays a key role in the promotion of drug resistance, the support of tumor progression, invasiveness, metastasis, and even the maintenance of a cancer stem-like phenotype. Here, we reviewed TME formation presenting it as a re...

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Bibliographic Details
Main Authors: Pablo Hernández-Camarero, Elena López-Ruiz, Juan Antonio Marchal, Macarena Perán
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-02022-5